GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs4747241 | 1 | rs4746112 | chr10:74042995 | DNAJB12 | chr10:74092588-74114907:- | 0.2 | 4.78 | 2.31E-6 | Heschl's gyrus morphology |
| THCA | cis | rs6479891 | 1 | rs4746119 | chr10:65129917 | LOC84989 | chr10:65224989-65226320:+ | 0.27 | 4.44 | 1.14E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746119 | chr10:65129917 | NRBF2 | chr10:64893007-64914785:+ | 0.28 | 4.67 | 3.88E-6 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746138 | chr10:65241741 | LOC84989 | chr10:65224989-65226320:+ | 0.25 | 4.08 | 5.18E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746138 | chr10:65241741 | NRBF2 | chr10:64893007-64914785:+ | 0.26 | 4.32 | 1.92E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746149 | chr10:65257393 | LOC84989 | chr10:65224989-65226320:+ | -0.25 | -4.04 | 6.1E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746149 | chr10:65257393 | NRBF2 | chr10:64893007-64914785:+ | -0.24 | -4.09 | 4.96E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746195 | chr10:65307653 | LOC84989 | chr10:65224989-65226320:+ | 0.23 | 3.7 | 0.00024 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746195 | chr10:65307653 | NRBF2 | chr10:64893007-64914785:+ | 0.25 | 4.1 | 4.79E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746974 | chr10:64892052 | LOC84989 | chr10:65224989-65226320:+ | 0.27 | 4.47 | 9.93E-6 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746974 | chr10:64892052 | NRBF2 | chr10:64893007-64914785:+ | 0.27 | 4.55 | 6.73E-6 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746994 | chr10:64905324 | LOC84989 | chr10:65224989-65226320:+ | 0.27 | 4.36 | 1.62E-5 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs6479891 | 1 | rs4746994 | chr10:64905324 | NRBF2 | chr10:64893007-64914785:+ | 0.27 | 4.57 | 6.28E-6 | Arthritis (juvenile idiopathic) |
| THCA | cis | rs4747011 | 1 | rs4747011 | chr10:72114378 | NPFFR1 | chr10:72014714-72026148:- | -0.39 | -3.78 | 0.000178 | Brain connectivity |
| THCA | cis | rs6479891 | 1 | rs4747045 | chr10:64926482 | LOC84989 | chr10:65224989-65226320:+ | 0.27 | 4.33 | 1.86E-5 | Arthritis (juvenile idiopathic) |